active 1 month ago Functions of Ribosomes Public Group

Ribosomes are essential cellular structures that play a critical role in protein synthesis. They are often referred to as the “protein factories” of the cell. Here’s an overview of ribosome function.

Protein Synthesis (Translation):

Ribosomes facilitate the translation of messenger RNA (mRNA) into proteins. This process involves several key steps:
Initiation: The small ribosomal subunit binds to the mRNA molecule and the initiator transfer RNA (tRNA) carrying the first amino acid (usually methionine).
Elongation: The ribosome moves along the mRNA, and tRNA molecules bring amino acids to the ribosome, where they are linked together in the order specified by the mRNA. This elongation continues, adding amino acids to the growing polypeptide chain.
Termination: When the ribosome reaches a stop codon on the mRNA, the translation process is terminated. Release factors help disassemble the ribosome and release the newly synthesized protein.
Peptide Bond Formation:

Ribosomes catalyze the formation of peptide bonds between adjacent amino acids, which is a key chemical reaction in protein synthesis. This activity is facilitated by the rRNA component of the ribosome, making ribosomes ribozymes (RNA molecules with catalytic properties).
Monitoring and Quality Control:

Ribosomes help ensure that the correct tRNA molecules are brought in according to the codon sequence on the mRNA. This contributes to the fidelity of protein synthesis.

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